GLP-1 Medications, Explained

Plain-English guides to every major GLP-1 weight loss medication — how each works, what results to expect, real monthly costs, and the side effects to know about before your first consult.

Active ingredients

The two molecules behind every brand on the market.

Semaglutide

The GLP-1 receptor agonist behind Ozempic, Wegovy, and Rybelsus.

~15% of body weightWeekly injection (or daily oral)
Tirzepatide

The dual GIP/GLP-1 agonist behind Mounjaro and Zepbound — the strongest weight loss results on the market.

Up to ~22.5% of body weightWeekly injection

Brand names

What your prescription will actually say.

Ozempic

Weekly semaglutide injection for type 2 diabetes — the brand that made GLP-1s famous.

2 mg / weekWeekly injection pen
Wegovy

High-dose weekly semaglutide, FDA-approved for chronic weight management.

~15% of body weightWeekly injection pen
Mounjaro

Weekly tirzepatide injection for type 2 diabetes, with best-in-class A1C and weight results.

15 mg / weekWeekly injection pen
Zepbound

Weekly tirzepatide for weight management — the strongest FDA-approved weight loss medication.

Up to ~22.5% of body weightWeekly injection (pen or vial)

Not sure where to start?

Read the complete GLP-1 guide for the full category overview, or jump straight to comparing Ozempic vs Wegovy. When you are ready, find a verified clinic near you.

Educational content only — not medical advice. All GLP-1 medications require a prescription from a licensed provider.